Role of aminoguanidine and nicorandil in oxidative stress in streptozotocin- induced diabetes mellitus in rats
Abstract: The effect of aminoguanidine, nicorandil and their combination against oxidative stress in streptozotocin (STZ) - induced diabetes mellitus was assessed in rats by determining changes in blood glucose level, superoxide dismutase (SOD), catalase (CAT), reduced glutathione (GSH), malondialdehyde (MDA) and nitric oxide (NO) in healthy and experimentally induced diabetic rats. Besides, histhopathological examination of kidney and liver tissues was ... إقراء المزيد