omaima.abdelatef

Omyma Abd Elaziz Abd El-Latif Abd Allah

Professor - Staff member

Faculty of science

Address: Chemistry Department - Faculty of Science - Sohag University

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Publications Which contain the keyword: naphthyridine


Synthesis of Some New 1,8-Naphthyridines From N-(7-Chloro-5-Methyl-1,8-Naphthyridine-2-yl) Acetamide and 7-Amino-2-Chloro-4-Methyl-1,8-Naphthyridine
The first parent compound N-(7-chloro-5-methyl-1,8-naphthyridine-2- yl)acetamide was reacted with both of ethyl thioglycolate forming ethyl [{7-(acetylamino)-4-methyl-1,8-naphthyridine-2yl} sulfanyl] acetate and ethyl[(-7-amino-4-methyl-1,8- naphthyridine-2yl) sulfanyl] acetate and with thioacetamide to afford N-[5-methyl-7- sulfanyl-1,8-naphthyridine-2-yl] acetamide. The last product was used as an intermediate for the synthesis of different novel mercapto derivatives. The second parent compound 7- amino-2-chloro-4-methyl-1,8-naphthyridine was reacted with several active organic compound ... Read more

2018-09-24 11:16:28 Keywords naphthyridine,
Synthesis of Some New 1,8-Naphthyridines From N-(7- Chloro-5-Methyl-1,8-Naphthyridine-2-yl)Acetamide and 7-Amino-2-Chloro-4-Methyl-1,8-Naphthyridine
The first parent compound _N_-(7-chloro-5-methyl-1,8-naphthyridine-2-yl)acetamide was reacted with both of ethyl thioglycolate forming ethyl [{7-(acetylamino)-4-methyl-1,8-naphthyridine-2yl} sulfanyl] acetate and ethyl[(-7-amino-4-methyl-1,8-naphthyridine-2yl) sulfanyl] acetate and with thioacetamide to afford _N_-[5-methyl-7-sulfanyl-1,8-naphthyridine-2-yl] acetamide. The last product was used as an intermediate for the synthesis of different novel mercapto derivatives. The second parent compound 7-amino-2-chloro-4-methyl-1,8-naphthyridine was reacted with several active organic compound (e.g. propanedinitrile, diethylpropanedioate, ethylcyanoacetate ... Read more

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