BACKGROUND: Hepatitis C virus infection is currently the most significant public health problem globally and particularly in Egypt. The outcomes of HCV infection range from asymptomatic chronic infection, with normal or nearly normal liver functions, to severe chronic hepatitis, evolving rapidly to cirrhosis and hepatocellular carcinoma. Our objective is to asses and evaluates the relationship between liver function tests, serum ... Read more

Starting with curcumin different pyrane, N-phenyl-1,3-thiazolidin and thiocurcumin derivatives were synthesized. 4-Oxo-3-phenyl1,3-thiazolidin derivative was reacted with different organic reagents examply, benzaldehyde, triethylorthoformate and hydrazine hydrate to form new series of 5-benzylidine-4-oxo-3-phenyl-1,3-thiazolidin, 5-ethoxymethylene-4-oxo-3-phenyl-1,3-thiazolidin and [1,8] naphthyridine derivatives. Some of these derivatives were evaluated as anti- inflammatory agents. All compounds have been characterized by spectral analyses. Read more