Synthesis and Biological activity of 1,3-Thiazolylidenehydrazinylidene ethylpyridiniumbromide monohydrate, 1,3- Thiazolylidenehydraziniumbromide and 1,3-Thiazolylidenehydrazine derivatives
1,3-Thiazolylidenehydrazinylidene ethylpyridinium bromide monohydrate, 1,3-thiazolylidenehydrazinium bromide and 1,3- thiazolylidenehydrazine derivatives were synthesized by heterocyclization of 2-(1-substituted ethylidene)hydrazinecarbothioamides, characterized and screened for their anti-bacterial activities. 3h showed the highest inhibitory effect against all types of bacterial compared to Moxifloxacin. The structures of synthesized compounds were established by spectroscopic (IR, 1H, 13C-NMR, Mass) and X-ray analyses. Read more