Genetic Polymorphism of Angiotensin Converting Enzyme and the Angiotensin II Type1 Receptor as Risk Factors in Patients with Chronic Kidney Disease
Abstract: Background: The rennin angiotensin system (RAS) is central to the pathogenesis of hypertension, cardiovascular disease and kidney disease. Angiotensin converting enzyme (ACE) and angiotensin II type 1 receptor (AT1R) are two of the main components of the RAS. The genetic polymorphisms of these key components provide a basis for studying the relationship between genetic variants and the development of ... Read more