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Antar Ahmed Abdelhamid

Assistant Professor - استاذ مساعد

Faculty of science

Address: Dr.

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Publications Which contain the keyword: Anti-inflammatory agents


Synthesis and anti-inflammatory study of novel N-substituted hydroacridine-1,8-diones and bis-hexahydroacridine-1,8-dione derivatives.
We report in this study the synthesis of some new N-substituted hexahydro- acridine-1,8-dione compounds including some new N- 2-hydroxypropylhexahydro-acridine-1,8-diones and their tosylatedocta- hydroacridine-1,8-dione derivatives in addition to some bis-hexahydro- acridine-1,8-diones via a one pot reaction technique. Moreover, in vivo anti-inflammatory evaluation for some newly synthesized compounds has been investigated. The highly alkylated bishydroacridine-1,8-dione 5f showed a higher anti- inflammatory potency ... Read more

Synthesis and Anti-inflammatory Study of Novel N-substituted Hydro-acridine-1,8-diones and Bis-hexahydroacridine-1,8-dione Derivatives
We report in this study the synthesis of some new N-substituted hexahydro- acridine-1,8-dione compounds including some new N- 2-hydroxypropylhexahydro- acridine-1,8-diones and their tosylatedoctahydro-acridine-1,8-dione derivatives in addition to some bis-hexahydroacridine-1,8-diones via a one pot reaction technique. Moreover,in vivo anti-inflammatory evaluation for some newly synthesized compounds has been investigated. The highly alkylated bis-hydroacridine-1,8-dione 5f showed a higher anti- inflammatory potency more than ... Read more

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