Morpholinium hydrogen sulfate (MHS) ionic liquid  as an efficient catalyst for the synthesis of bio-active multi-substituted imidazoles (MSI) under  solvent-free conditions
Morpholinium hydrogen sulfate as an ionic liquid was employed as a catalyst for the synthesis of a biologically active series of multi-substituted imidazoles by a four-component reaction involving the combination of benzil with different aromatic aldehydes, ammonium acetate, and 1-amino-2-propanol under solvent-free con-ditions. The key advantages of this method are shorter reaction times, very high yield, and ease of processing. ... إقراء المزيد