Women with reast cacer require information to help them ange their illness, it assist patients in maing treatment decisions and maging immediate effects of treatment Read more

ABSTRACT Background: Primary tumor resection in metastatic breast cancer (MBC) remains a palliative procedure. Its impact as an upfront option on survival is debatable. No data from our locality addressed this issue; we conducted this retrospective study to ex- plore its benefit as regards time-to-progression and/or time-to-death. Methods: Data of patients’ medical records used between 2010 through 2015 from Sohag ... Read more

Background: Primary tumor resection in metastatic breast cancer (MBC) remains a palliative procedure. Its impact as an upfront option on survival is debatable. No data from our locality addressed this issue; we conducted this retrospective study to ex- plore its benefit as regards time-to-progression and/or time-to-death. Methods: Data of patients’ medical records used between 2010 through 2015 from Sohag Cancer ... Read more

Breast reconstruction by use of latissmus myocutaneus flap is common use Read more

Abstract Background: Limited research on psychiatric disorders prevalence among Upper Egyptian women treated for breast cancer. To our knowledge, no studies published earlier from our locality considering this issue. Purpose: To explore the prevalence of anxiety and depression in a sample of women treated for breast cancer and to find possible associated factors for these disorders. Design: A cross-sectional observational ... Read more

_ABSTRACT_ INTRODUCTION: Breast cancer (BC) is most common cancer site in women worldwide. The CA 15-3 is tumor associated antigen which detects soluble forms of MUC-1 protein. In normal breast tissue MUC-1 is expressed in the duct and acini, but with neoplastic transformation normal cell polarization and tissue architecture is disrupted leading to shedding of MUC-1 in the blood, where ... Read more

_ABSTRACT_ INTRODUCTION: Breast cancer (BC) is the most common malignant tumor in females in almost all of countries with highest age-adjusted incidence in developed countries (73%) and includes the 23% of all types of cancers. World Health Organization (WHO) report shows that this prevalence rising 2% per year. As a matter of fact, BC is responsible for most of deaths ... Read more

Identification of metastatic potential of breast cancer cells is necessary for proper management of this disease. This work aimed to estimate likelihood of axillary lymph node (ALN) involvement in breast cancer patients based on human epidermal growth factor receptor 2 (HER2) expression. Primary tumors of 317 breast cancer patients were evaluated for estrogen receptor (ER), progesterone receptor (PR) and HER2 ... Read more

Background and Aim: β-catenin is a cell membrane mol-ecule that is essential for cell-cell adhesion of normal epithelia. It is down-regulated in several epithelial tumors and its expression is correlated with tumor cell invasion and metasta-sis. The aim of this study was to evaluate expression status and angiogenic effect of β-catenin in locally aggressive mammary carcinoma. Methods: Formalin-fixed paraffin embedded ... Read more

Background: Breast cancer is the first most common malignancy in Egyptian females. Oxidative stress is considered to be involved in the pathophysiology of all cancers, especially breast cancer. An inappropriately low rate of apoptosis can give rise to cancer. Objectives: The purpose of this study was to asses, compare and correlate the circulatory levels of some oxidants (malondialdehyde "MDA" and ... Read more