Intestinal parasitic infestations are endemic worldwide especially in developing countries. The aim of this study is to determine the prevalence of common intestinal parasitic infestations in rural Sohag and factors affecting it. This cross sectional study has been conducted in Zewak Sharqia village, El-Monshaa district, Sohag Governorate, Egypt from August 2010 up to March 2011. A random sample of 516 persons was taken. Data was collected and stool samples were taken. Two hundred and eighty four (55%) of studied population were infested by intestinal parasites. The intestinal parasites that detected were Exuris (21.7%), Amoebiasis (13.2%), Giardiasis (9.9%), H. nana (9.9%), S. mansoni (0.2%), and Ascariasis (0.2%). Infection rates were significantly higher in children less than 12 years (63.31%), persons with low socioeconomic status (82.10%), using pumped water (79.82%), did not wash vegetable and fruits (90.44%) , did not receive health education (88.32%), did not visit doctor regularly (76.92%) and who were underweight (100%). Higher infection rate was independently associated with age less than 12 years (odds ratio= 2.37 CI=1.17-4.79), low Socioeconomic status (odds ratio= 12.60, CI=5.66-28.08), not wash fruits and vegetables (odds ratio = 2.65, CI=1.19-5.91), not receiving health education (odds ratio =3.54, CI =1.56-8.04) and not visiting doctor regularly (odds ratio=7.78, CI = 3.21-18.85). Gender and source of water were not independently risk factors for higher infection. [Ahmed Fathy Hamed, Fouad M. A. Yousef, Eman Khalaf Omran and Amal Moustafa. Common Parasitic Infestation among Rural