Introduction: Ventilator associated pneumonia (VAP) is the most prevalent infectious problem in ICU and is associated with high morality, longer stay in the ICU and in hospital, increased antibiotic use and greater hospital costs.
Aim of the Work: Estimate the incidence of Ventilator-associated pneumonia (VAP), Identify risk factors associated with acquiring the infections and identify the types of pathogens causing (VAP) and their antimicrobial resistance patterns in ICU of Sohag university hospital.
Patients and Methods: The study included 109 ICU patients according to the defined inclusion criteria, VAP was diagnosed according to CDC surveillance definition.
Results: Thirty three patients were diagnosed as VAP. The overall infection/IOO patients was 3028,
the infection rate/ 1000 device-days was 51.08 and mean VAP diagnosis time was 7days, Thirty-seven
microorganisms were isolated from . The most commonly isolated microorganisms were Staphylococcus aureus in 13 cases (35%) of all isolates. Sepsis/septic shock, male gender and COPD were the most serious risk factor increasing VAP.
Conclusion: VAP infection rate is high in our ICU, Male patients; patients with sepsis, COPD, renal failure and liver cirrhosis are at higher risk for VAP. Previous use of antibiotics and tracheostomy increase risk of VAP. Isolated organisms show high antibiotic resistance rate.