Introduction: Portal hypertensive gastropathy (PHG) is an important cause of morbidity in patients with Liver cirrhosis (LC). Helicobacter pylori (HP) infection is a common cause of gastritis and is an endemic disease in Egypt.
Aim of the work: to investigate the relationship of H pylori infection and portal hypertensive gastropathy (PHG) in liver cirrhosis (LC).
Material and Methods: Fifty patients with LC including 25 cases with PHG and 25 cases without PHG who attended Sohag Faculty Hospital during the period 9/2016-3/2017 were examined for the presence of H pylori infection histologically using Hematoxyline and Eosin and Geimsa stains. The correlation between HP infection and the severity of PHG was studied statistically.
Results: H pylori were detected in 76% of cases of LC (72% in LC with PHG and 80% of cases LC without PHG). Although there was an association between H pylori infection and the severity of PHG (5/7 cases), there was no statistically significant difference between H pylori infection and PHG.
Conclusion: H pylori infection can be seen in cases of LC irrespective of the presence or absence of PHG.Keywords: H pylori, PHG, Liver cirrhosis.