Reaction of 2-guanidinobenzimidazole with halogenated active methylenes and ketones gave dihydroimidazole
and 3,4-dihydrobenzo[4,5]imidazo [1,2-a][1,3,5]triazin derivatives in very good yield. The
anti-bacterial evaluation of the newly synthesized products against broad spectrum of bacteria was
performed. Most of products showed high inhibitory effect. All compounds have been characterized
based on IR, 1H NMR, 13C NMR and Mass spectra.