ARTICLE INFO ABSTRACT Aim of the work timing of presentation and surgical interference. Patients and methods University Hospital from July 2010 to April 2014. Necrotizing fasciitis (NF) was diagnosed clinically and confirmed by intraoperative findings and routine postoperative histopathological criteria in association to laboratory values e.g. total leucocytic count; band leucocytes percentage and serum Na were recorded. According to these criteria, patients were classified into 2 groups: group A; 26 patients with objective crite group). Results: respect to pain, tense edema, bullae, skin discoloration and crepitation (P= 0.04, and 0.045 respectively). Elevated WBCs >15.4 ×10 of group B (and 6.61% of group B (p=0.0001). Serum Na<1 and B respectively ((A and the remaining 4 cases were subjected to major extremity amputations. The overall mortality was 27% (7 pa Among patients underlying early debridement within 12 hours of admission (n=17), there was 3 deaths (18%) versus 4 deaths out of 9 (44.4 %) were recorded in patients with de 0.05). Conclusion: reasonable surgical outcome. In patients with clinical suspicious, laboratory parameters include WBCs >15.4×10 helpful in early diagnosis.