Objective To evaluate the clinical and mycological cure
rates of a novel mixture consisting of Bee-honey and
yogurt compared to local antifungal agents for treating
patients with vulvo-vaginal candidiasis (VVC) during
pregnancy.
Materials and methods This is a prospective comparative
study which included 129 patients with VVC during
pregnancy. The participants were allocated into study
group (n = 82) who received a mixture of Bee-honey and
yogurt vaginally and control group (n = 47) who received
local anti-fungal agents. The Chi-square test was used to
evaluate the clinical and mycological cure rates and the
side-effects of both modes of therapy.
Results The clinical cure rate was significantly higher in
the study than the control group (87.8 vs. 72.3%, respectively) while the mycological cure rate was higher in the
control than the study group (91.5 vs. 76.9%, respectively).
Both types of therapy were favorably tolerated by most of
the patients. Side effects were reported only in 24.3 and
29.7% of patients in group I and II, respectively (p\ 0.05).
Conclusions The mixture of Bee-honey and yogurt produced a high clinical cure rate and a reasonable mycological cure rate. It can be used as a complementary or an
alternative to antifungal agents especially in patients with
VVC during pregnancy