Some optical parameters of Bi2Te2Se thin films, determined from the measured absorbance and transmittance at normal incidence in the visible spectral range, were studied as functions of film thickness and annealing temperature. These parameters were found to be sensitive to both film thickness and microstructure change caused by annealing in a film. The effect of thickness and temperature of annealing on the optical gap was interpreted in terms of elimination of defects and change of disordering in the amorphous matrix.