Here, we reported two methods for the synthesis of multi-substituted imidazoles,firstly via four-component cyclocondensation reaction of benzil, aliphatic amines (allylamine or pentylamine), and aromatic
aldehyde and ammonium acetate. Using an ionic liquid catalyst namely, diethyl ammonium hydrogen sul-fate, and under solvent-free conditions. Secondly, via the alkylation of synthesized NH imidazoles with alkyl
halide (allyl bromide and pentyl bromide) gave8a–cin high yield (average 90%), the products can be puri-fied by a non-chromatographic method, and these newly synthesized compounds have been characterized by
spectral data: FTIR, IR,
C nuclear magnetic resonance, the elemental analysis, and the X-ray structure.