Common etiologies of peripheral nerve injury include penetrating injury, crush, stretch, and ischemia. Management of nerve injury requires familiarity with the relevant anatomy, pathology, pathophysiology, and the surgical principles, approaches and concerns. Surgical repair is done at varying time intervals after the injury, and there are a number of considerations in deciding whether and when to operate. Repair of peripheral nerve injuries continues to be a major challenge in reconstructive surgery. Satisfactory functional recovery after a peripheral nerve injury is dependent on accurate regeneration of axons to the original end organs.
Reconstruction of peripheral nerve injuries has improved particularly over the last two decades with the experience in traumatic nerve injuries.
Epineurial repair has been the standard method for many years and still has a prominent place in nerve injuries today and fibrin glues have been used as an alternative to micro-sutures to maintain coaptation.
This study compares between epineurial microsuturing and fibrin glue in repair of peripheral nerve injuries and shows that the use of fibrin glue gives an equal or slightly better results than microsuturing in repair of peripheral nerve injuries.