Background To evaluate the efficacy and safety of 25-
gauge transconjunctival sutureless vitrectomy (25-G TSV)
in the management of vitreoretinal complications of
proliferative diabetic retinopathy (PDR).
Methods A retrospective review of a noncomparative
interventional case series including 200 eyes of 164
consecutive patients who underwent 25-G TSV for the
management of PDR was performed. The main outcome
measures were preoperative and postoperative visual acuity
and intraocular pressure (IOP), the surgical success rate,
and intraoperative and postoperative complications. All
cases had a follow-up period of at least 6 months.
Results The mean logarithm of the minimum angle of
resolution (LogMAR) visual acuity was significantly
improved from 1.55 preoperatively to 0.72 at the final
visit. No intraoperative complications related to the 25-G
TSV procedure were recorded. Transient hypotony was
recorded in 18 eyes (9%) on postoperative day 1 and 15
eyes (7.5%) on postoperative day 5. Two of these eyes (1%)
had choroidal detachment on postoperative day 5. One case
showed bacterial endophthalmitis after the second surgery.
The single operation and final surgical success rates were
81.5% and 98% respectively.
Conclusion These outcomes of 25-G TSV showed its
safety and efficacy in the management of PDR.