Introduction: Ventilator associated pneumonia (VAP) is the most prevalent infectious problem in ICU and
is associated with high mortality, longer stay in the ICU and in hospital, increased antibiotic use and greater
hospital costs.
Aim of the Work: Estimate the incidence of Ventilator-associated pneumonia (VAP), Identify risk factors
associated with acquiring the infections and identify the types of pathogens causing (VAP) and their
antimicrobial resistance patterns in ICU of Sohag university hospital.
Results: Thirty three patients were diagnosed as VAP. The overall infection/100 patients was 30.28,
the infection rate/1000 device-days was 51.08 and mean VAP diagnosis time was 7days, Thirty-seven
microorganisms were isolated from .The most commonly isolated microorganisms were Staphylococcus
aureus in 13 cases (35%) of all isolates. Sepsis/septic shock, male gender and COPD were the most serious
risk factor increasing VAP.and liver cirrhosis are at higher risk for VAP. Previous use of antibiotics and tracheostomy increase risk of VAP. Isolated organisms show high antibiotic resistance rate