Results of our study revealed that patients showed significantly decreased pressure gradient across PVS immediately post-BPV (85.58 ± 15.9 mmHg to 17 ± 13 mmHg) (p < 0.001). The procedure was ineffective only in eight (12.7%) children of whom five had re-BPV and three were operated on. Subpulmonary stenosis was seen in 4.8% of children pre-BPV; in 15% post-BPV and in only 3.5% at the end of follow-up. Complications were seen in two (3.2%) patients including one case of a balloon being lodged in the iliac vein (surgical repair) and another patient had perforation of RV during contrast injection with moderate pericardial effusion which resolved spontaneously. Follow-up echocardiography results were similar to those of immediate post BPV values of pressure gradients across PVS. Pulmonary regurgitation > II increased from 2.2% before to 24% after BPV. These medium-term follow-up data confirm efficacy and safety of BPV in children with isolated PVS.