®Avian influenza (AI) is an infectious viral disease of birds

®Some of these AI viruses have  been reported to cross the species barrier and cause disease or subclinical infections in humans and other mammals.

® Avain virus subtype (H5N1) is a highly pathogenic AI virus, re-emergence occur in 2003 and 2004.

®The case fatality rate for H5N1 infections in people is much higher compared to that of seasonal influenza infections.