žRichard Bright (1836): first observed that anemia was a complication of renal failure.

žRobert Christison: further described renal anemia.

žMiyake (1977): purified and identified Epo.

žEschbach (Dec 2, 1985): first human use of  EPO

žRichard Bright (1836): first observed that anemia was a complication of renal failure.

žRobert Christison: further described renal anemia.

žMiyake (1977): purified and identified Epo.

žEschbach (Dec 2, 1985): first human use of  EPO