Course Matrix of Designing of Toxicological Studies in Forensic Medicine &Clinical Toxicology

Topic

 

Objective (s)

 

Learning strategy

 

  Devices & Methods

  

Dose response relationship

 

Gain the basic knowledge of:

Dose response relationship

 

- Lectures

- practical lessons

-Assigment

Computer for electronic  lectures

Microscope, slides in department laboratory.

  Duration of toxicity studies, acute ,subacute, chronic

 

 

Gain the basic knowledge of:

Duration of toxicity studies, acute ,subacute, chronic

- Lectures

- practical lessons

-Assigment

Computer for electronic  lectures

Microscope, slides in department laboratory.

  Testing for acute and chronic toxicity

 

 

Gain the basic knowledge of:

Testing for acute and chronic toxicity

-Lectures

- practical lessons

-Assigment

Computer for electronic  lectures

Microscope, slides in department laboratory.

 

Selection of animal species and dose level

 

Gain the basic knowledge of:

Selection of animal species and dose level

 

- Lectures

- practical lessons

-Assigment

Computer for electronic  lectures

Microscope, slides in department laboratory.

 

principles of acute oral, skin, inhalation, tests.

 

Gain the basic knowledge of:

 

principles of acute oral, skin, inhalation, tests.

 

-Lectures

- practical lessons

-Assigment

Computer for electronic  lectures

Microscope, slides in department laboratory.

  

Pathological techniques in toxicology

 

Gain the basic knowledge of:

Basic techniques in autopsy and practice

Methods applicable to specific organ systems

Skin subcutaneous tissue

Mammary gland

Pulmonary system

Cardiovascular system

Digestive system

Urinary system

Nervous system

Special sense organs

 

- Lectures

- practical lessons

-Assigment

Computer for electronic  lectures

Microscope, slides in department laboratory.

  Hematology and clinical chemistry in toxicology studies

 

 

Gain the basic knowledge of:

 

Preanalytical  variables

Analytical procedures

Liver, kidney, heart

Gastrointestinal tract

Plasma proteins

Endocrine system

Blood cell hematopesis

Hematoxic effects

 

-Lectures

- practical lessons

-Assigment

Computer for electronic  lectures

Microscope, slides in department laboratory.

 Antidotal studies

 

 

Gain the basic knowledge of:

Def. of poison and antidote

Mechanism of antidotal action

Antidotes act chemically

Antidotes tat act pharmacologically

Functional type

Assessment of antidotal efficacy

Assessment of antidotes in experimental animals

Assessment of antidotes in human beings

- Lectures

-Assigment

Computer for electronic  lectures

 

Evaluation of toxicity in human subjects

 

Gain the basic knowledge of:

Types and sources of toxicity

Dose and time related effect

Attribution of cause

Evaluation of toxicity

Evaluation by experimental studies

Evaluation by observational studies

Voluntary reporting schemes

Prescription event monitoring

Medical record linkage

Hospital based monitoring system

Information sources in evaluation of toxicity

- Lectures

- practical lessons

-Assigment

Computer for electronic  lectures

Microscope, slides in department laboratory.

Ethics of animal research

 

Gain the basic knowledge of:

Basic guiding in use of animal in toxicology

Sign of suffering in animals

Sign of moribundity

Principles for humane ttt of animal in studies

- Lectures

-Assigment

Computer for electronic  lectures