Three Lectures 2 hours each
Two hours Practical Slide Microscopic Examination for Studends of Pathology
By the end of the course Students should Learn
TUMORS OF THE MEDIASTINUM (A)
THYMOMA AND THYMIC CARCINOMACARCINOMA
Classification of Thymic Tumors
Thymoma and Thymic Carcinoma
General Features
Thymoma
Fine-needle aspiration
Pathologic Features of Thymoma
Grossly
“Microthymomas”
Microscopically
By electron microscopy
Immunohistochemistry
Classification of Thymoma and Thymic Carcinoma
The subtypes of thymomas included in the WHO classification
Type A Thymoma (Spindle Cell; Medullary)
Type AB Thymoma (Mixed)
Type B1 Thymoma (Lymphocyte-Rich; Lymphocytic; Predominantly Cortical; Organoid)
Type B2 Thymoma (Cortical)
Type B3 Thymoma (Epithelial; Atypical; Squamoid; Well-Differentiated Thymic Carcinoma)
Rare subtypes of thymoma that do not easily fit into the A-B nomenclature include
Micronodular thymoma
Metaplastic thymoma
Microscopic thymoma (nodular hyperplasia)
Cytology
Limitations of the procedure
Thymic Carcinoma
Thymic tumor
Thymic Carcinoma
Differences from other conventional types of thymoma
Diagnosis
Squamous Cell Carcinoma (SCC)
Basaloid Carcinoma
Differential diagnosis
Mucoepidermoid Carcinoma
Lymphoepithelioma-Like Carcinoma
Clear cell carcinoma
Sarcomatoid Carcinoma (Carcinosarcoma)
Adenocarcinomas
NUT (midline) carcinoma
Undifferentiated (Anaplastic) Carcinoma