عبدالرحيم محمد احمد محمود

مدرس -

كلية العلوم

العنوان: جامعة سوهاج - كلية العلوم - قسم الكيمياء



المنشورات و المؤلفات التي تحتوي علي الكلمة المفتاحية: Pyrimidine

2018-09-20 10:59:25 الكلمات المفتاحية Pyrimidine, Dihydropyrimidinon,
Rapidly and Highly Yielded Synthesis of Pyrimidine, Dihydropyrimidinone, and Triazino[2,1‐b]quinazolin‐6‐ones Derivatives
The reaction of 4‐oxo‐3,4‐dihydroquinazolinyl‐2‐guanidine 1 with several active methylene compounds has revealed formation of the corresponding hydropyrimidine and dihydropyrimidnone (DHPMs) derivatives via cycloaddition reaction mechanism. Satisfactory results were obtained with good yields, short time, and simplicity in the experimental procedure. Reaction with ketones in DMF proceeded via (5+1) heterocyclization and resulted in the formation of 2‐amino‐4‐(het)aryl‐4,6‐dihydro‐1(3)(11)H‐[1,3,5] triazino[2,1‐b]quinazolin‐6‐ones 8‐13, respectively. All ... إقراء المزيد

2018-09-18 21:57:39 الكلمات المفتاحية PASS INET, fused pyridine, pyrrazole, Pyrimidine, pyrrole, pyridine, phase transfer catalysis,
Synthesis  of  Some  New F used  P yridines  and  Prediction  their  Biological Activity via PASS INET
A new series of fused heterocyclic compounds containing pyridine moieties were prepared via the reaction of 2-amino-6-(methylthio)-4-phenylpyridine-3,5-dicarbonitrile with some halo reagents, active methylenes, acetic anhydride, phenylisothiocyanate, hydrazine hydrate or thioacetamide. Accompanied with Predictions of the activity spectra of some selected compounds using PASS INET.at Pa > 70%, showing high probability of Atherosclerosis treatment, Antineoplastic, DNA intercalator, Protein kinase inhibitor and ... إقراء المزيد