Background: Aspartame is one of the most widely used artificial sweeteners in over
90 countries worldwide in over 6000 products, including carbonated and powdered
soft drinks, hot chocolate, chewing gum, candy, desserts, yogurt, and tabletop
sweeteners, as well as some pharmaceutical products like vitamins and sugar-free
cough drops. Aspartame has been shown to induce oxidative stress and lipid
peroxidation; most serious effects result from chronic exposure due to these effects.
Also it shows organ and species toxicity with relation to the liver, kidney, brain, testis
and other organs. The aim of this study is to spotlight on aspartame, the most widely
used artificial sweetener regarding benefits and Hazards. This essay was conducted by
reviewing the literature, researches, and textbooks dealing with aspartame.
Conclusion: We found that aspartame is a good& beneficial artificial sweetener; FDA
approved a safe daily dosage of 40 mg/kg/ day regarding diabetes and obesity.
Harmful if used in larger doses regarding neurobehavioral, hepatic, testicular and
other organ dysfunction, however it has no effects on breastfeeding or carcinogenic
effects.Therfore, the role of physicians is to adjust the dose of aspartame to that
which approved by FDA and do more clinical studies to detect more benefits and