_ABSTRACT_ INTRODUCTION: Breast cancer (BC) is the most common malignant tumor in females in almost all of countries with highest age-adjusted incidence in developed countries (73%) and includes the 23% of all types of cancers. World Health Organization (WHO) report shows that this prevalence rising 2% per year. As a matter of fact, BC is responsible for most of deaths ... إقراء المزيد

_ABSTRACT_ INTRODUCTION: Breast cancer (BC) is most common cancer site in women worldwide. The CA 15-3 is tumor associated antigen which detects soluble forms of MUC-1 protein. In normal breast tissue MUC-1 is expressed in the duct and acini, but with neoplastic transformation normal cell polarization and tissue architecture is disrupted leading to shedding of MUC-1 in the blood, where ... إقراء المزيد