mohammed.sherif

Mohammed Sherif Saddik

Lecturer -

Faculty of Pharmacy

Address: faculty of pharmacy

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In vitro and in vivo characterization of domperidone-loaded fast dissolving buccal films‏

2020 | Keywords Polyvinylpyrrolidone, Buccal films, Domperidone, Bioavailability, Pharmacokinetics,
In vitro and in vivo characterization of domperidone-loaded fast dissolving buccal films‏
The delivery of drugs via fast dissolving films is an effective alternative for drugs with low bioavailability when administered by other routes. This is the case of domperidone (DMP) an anti-emetic drug with low water solubility and vulnerable to extensive first-pass effect. To overcome these limitations, in this work, we designed and produced fast dissolving muco-adhesive buccal films of domperidone ... Read more

A NOVEL TREATMENT OF FRECKLES BY PHOTODYNAMIC THERAPY USING CHITOSAN-METHYLENE BLUE HYDROGEL

2015 | Keywords freckles, methylene blue,
A NOVEL TREATMENT OF FRECKLES BY PHOTODYNAMIC THERAPY USING CHITOSAN-METHYLENE BLUE HYDROGEL
Objective: To evaluate the efficacy of chitosan- methylene blue (MB) hydrogel mediated photodynamic therapy in the treatment of freckles. Patients and methods: Thirty four patients complaining from freckles were recruited in this Prospective, split-face controlled study. Pregnant women, patients with photosensitive dermatosis, other contraindications for phototherapy and use of topical or systemic retinoid treatment in the past 6 months were ... Read more

DEVELOPMENT AND CLINICAL EVALUATION OF SOME TOPICAL PHARMACEUTICAL DOSAGE FORMS OF PHENYTOIN.

2014 | Keywords Phenytoin patch, cream, oint.,
DEVELOPMENT AND CLINICAL EVALUATION OF SOME TOPICAL PHARMACEUTICAL DOSAGE FORMS OF PHENYTOIN.
Phenytoin ( diphenlhydantoin), a hydantoin derivatives that has long been for its use in epilepsy, Clinical data indicate that systemic or topical phentoin enhances the healing of various types of wounds and chronic ulcers. This pushes us to formulate and optimize some topical dermatological formulations containing phentyoin (PHT) or its sodium salt for treatment of certain skin healing. Dermal films, ... Read more

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