eman_shalabi

Eman Muhammad Salah El-Deen Muhammad Shalabi

Professor - Professor Emeritus of Pathology

Faculty of medicine

Address: القوصية - محافظة أسيوط

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Upper and lower gastrointestinal endoscopy in children attending Sohag University Hospital: Indications and results

2006 | Keywords GIT, Endoscopy, pediatrics,
Upper and lower gastrointestinal endoscopy in children attending Sohag University Hospital: Indications and results
BACKGROUND: The development of endoscopic instruments to evaluate different parts of the gastrointestinal tract improved significantly the information about diseases affecting the gastrointestinal tract, and its management. METHODS: The study included 197 children referred for endoscopic examination during the period of October 2002 to September 2005, aged from 3 months to 16 years (average 5.7 years) and 55% of them ... Read more

Supraglottic Cyst as a Rare Pathology

2006 | Keywords Supraglottic cyst,
Supraglottic Cyst as a Rare Pathology
Cysts of the larynx are rare lesions, most frequently located on the supraglottic region. This study included eight cases with supraglottic cyst. Five cases were males with an age average of 32 year old (22-60 years). Two cases were females with an age average of 28 years (20, 36 years respectively). One case was a boy, 8 years old The ... Read more

Immunohistochemical expression of bcl-2 in normal, dysplastic, pre-invasive and invasive oesophageal squamous cell carcinoma and its prognostic value

2005 | Keywords squamous cell carcinoma,
Immunohistochemical expression of bcl-2 in normal, dysplastic, pre-invasive and invasive oesophageal squamous cell carcinoma and its prognostic value
Cancer of the oesophagus ranks as the ninth most common malignancy in the world, and recent evidence shows that its incidence is increasing. Prognosis of this disease is poor, with an overall 5-year survival rate of less than 10%. Bcl-2 proto-oncogene is a known inhibitor of apoptosis with special importance in the development, progression and prognosis of various human cancers. ... Read more

Expression of Cell Adhesion Molecule (CD44v6) in Thyroid Lesions and its Significance

2005 | Keywords Adhesion Molecule, CD44v6, Thyroid,
Expression of Cell Adhesion Molecule (CD44v6) in Thyroid Lesions and its Significance
ABSTRACT AIMS: This work was performed to study the expression of CD44v6 in several non-neoplastic and neoplastic thyroid lesions with special focus on its potential differential diagnostic value in differentiating between benign and malignant thyroid lesions and to evaluate its possible prognostic value in thyroid carcinoma METHODS AND RESULTS: This study included 56 cases of thyroid lesions; eight of them ... Read more

Diagnostic accuracy of Helicobacter pylori stool antigen test (HpSA) and gastric-expression of MUC2 & MUC5AC in patients with dyspepsia

2005 | Keywords Helicobacter pylori stool antigen, HpSA, gastric, MUC2, MUC5AC, dyspepsia,
Diagnostic accuracy of Helicobacter pylori stool antigen test (HpSA) and gastric-expression of MUC2 & MUC5AC in patients with dyspepsia
ABSTRACT _Helicobacter pylori__(H. pylori)_ infection is one of the most common causes of gastritis and peptic ulcer diseases. A risk association between _H pylori_ infection and the development of gastric adenocarcinoma and mucosa associated lymphoid tissue lymphoma has been established. _H. pylori_ reside in the gastric mucus layer of the superficial epithelium, attachs to gastric epithelial cells and mucins are ... Read more

Estradiol metabolites attenuate monocrotaline-induced pulmonary hypertension in rats

2005 | Keywords Estradiol, monocrotaline, pulmonary hypertension, rats,
Estradiol metabolites attenuate monocrotaline-induced pulmonary hypertension in rats
ABSTRACT: Pulmonary arterial hypertension (PH) is a deadly disease characterized by pulmonary arterial vasoconstriction and hypertension, pulmonary vasculature remodeling, and right ventricular hypertrophy. Our previous in vivo studies, performed in several models of cardiac, vascular, and/or renal injury, suggest that the metabolites of 17beta-estradiol may inhibit vascular and cardiac remodeling. The goal of this study was to determine whether 2-methoxyestradiol ... Read more

Quantitative comparison of infected Schistosomiasis mansoni and Haematobium: animal model analysis of the granuloma cell population

2005 | Keywords granuloma, : animal model, Haematobium, Mansoni, Schistosomiasis,
Quantitative comparison of infected Schistosomiasis mansoni and Haematobium: animal model analysis of the granuloma cell population
To evaluate the hypothesis that the granuloma cell population in S. haematobium is different from that of S. mansoni infections, a hamaster animal model was established. Infection of hamesters was induced by abdominal skin exposure of male golden hamsters with 300 cercariae. S. haematobium granuloma cell population in the small intestine, urinary bladder, liver and spleen and those of S. ... Read more

First record of Schistosoma intercalatum in Upper Egypt, an abnormal locality and presentation simulating lymphoma

2005 | Keywords simulating lymphoma, abnormal locality, Upper Egypt, Schistosoma intercalatum,
First record of Schistosoma intercalatum in Upper Egypt, an abnormal locality and presentation simulating lymphoma
Abstract Schistosomiasis due to _Schistosoma intercalatum_ is highly restricted to the Western regions of equatorial Africa. Its main clinical manifestation is rectal bleeding. A case is described of a 14 year old boy living in Upper Egypt who was presented to General Surgery Department, Sohag University Hospital, South Valley University, complaining of vague abdominal pain, rectal bleeding, multiple abdominal masses ... Read more

Attenuation of renal injury in db/db mice overexpressing superoxide dismutase: evidence for reduced superoxide-nitric oxide interaction

2004 | Keywords superoxide-nitric oxide, superoxide dismutase, db/db mice, Renal injury,
Attenuation of renal injury in db/db mice overexpressing superoxide dismutase: evidence for reduced superoxide-nitric oxide interaction
ABSTRACT: The effects of overexpression of Cu(2+)/Zn(2+) superoxide dismutase-1 (SOD-1) on indexes of renal injury were compared in 5-month-old nontransgenic (NTg) db/db mice and db/db mice hemizygous for the human SOD-1 transgene (SOD-Tg). Both diabetic groups exhibited similar hyperglycemia and weight gain. However, in NTg-db/db mice, albuminuria, glomerular accumulation of immunoreactive transforming growth factor-beta, collagen alpha1 (IV), nitrotyrosine, and mesangial ... Read more

Laparoscopic versus cholecystectomy for acute calculus cholecyctitis: Which is better?

2004 | Keywords Laparoscope, cholecystectomy, acute calculus cholecyctitis,
Laparoscopic versus cholecystectomy for acute calculus cholecyctitis: Which is better?
BACKGROUND: Laparoscopic cholecystectomy (LC) has become the treatment of choice for elective cholecystectomy, but controversy persists over use of this approach in the treatment of acute calculous cholecystitis. AIM OF THE STUDY: To assess the feasibility, safety, and outcome of laparoscopy in management of patients with acute calculous cholecystitis and to determine whether it is a boon or bust in ... Read more