_ABSTRACT _ BACK GROUND: Cervical spine involvement in patients with rheumatoid arthritis (RA) can cause pain and disability, with a variety of neurologic signs and symptoms. OBJECTIVES: To investigate the relationship between structural cervical spine involvement in patients with RA with the age at disease onset and the degree of radiologic severity of RA measured by Larsen scoring. PATIENTS AND ... Read more

_TEXT _ BACKGROUND: We describe 4 cases: Three male brothers, the oldest one (20 years) and the younger brothers (15 and 12 years), the fourth case (21 years) female, from the same city (Dar El-Salam); Sohag Governorate, Upper Egypt, presented with cutaneous hypergimentation accompanied by hypertrichosis and induration, acquired hand and foot deformities (hallux valgus), low height, hearing loss, hepatosplenomegaly ... Read more