PURPOSE:BACKGROUND: BEVACIZUMAB IS ONE OF THE ANTI VASCULAR ENDOTHELIAL GROWTH FACTOR (ANTI-VEGF) AGENTS WHICH HAS ANTIANGIOGENIC AND OEDEMA-DIMINISHING ACTIONS. IT IS USED WIDELY AS AN INTRAVITREAL SOLUTION TO DIMINISH NEW VESSELS FORMATION AND REDUCE THE OEDEMA OF THE OCULAR DISEASES. OBJECTIVES: TO EVALUATE THE SAFETY OF AN INTRAVITREAL INJECTION OF BEVACIZUMAB ON THE CEREBRAL CORTEX OF RAT. MATERIAL AND METHODS: ...
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