ghada_galal

Ghada Galal

Professor - Head of Tropical Medicine and Gastroenterology Department

Faculty of medicine

Address: Sohag, Egypt

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Publications Which contain the keyword: 4-dihydroxybenzoic acid

β-RA reduces DMQ/CoQ ratio and recues the encephalopathic phenotype in Coq9R239X mice

2019-09-17 11:47:05 Keywords , 4-dihydroxybenzoic acid, 2, 4-dihydroxybenzoic acid, astrogliosis, mitochondrial encephalopathy, Q synthome, spongiosis,
β-RA reduces DMQ/CoQ ratio and recues the encephalopathic phenotype in Coq9R239X mice
Coenzyme Q (CoQ) deficiency has been associated with primary defects in the CoQ biosynthetic pathway or to secondary events. In some cases, the exogenous CoQ supplementation has limited efficacy. In the Coq9R239X mouse model with fatal mitochondrial encephalopathy due to CoQ deficiency, we have tested the therapeutic potential of b-resorcylic acid (b-RA), a structural analog of the CoQ precursor 4-hydroxybenzoic ... Read more

β-RA reduces DMQ/CoQ ratio and recues the encephalopathic phenotype in Coq9R239X mice

2019-09-17 11:47:05 Keywords , 4-dihydroxybenzoic acid, 2, 4-dihydroxybenzoic acid, astrogliosis, mitochondrial encephalopathy, Q synthome, spongiosis,
β-RA reduces DMQ/CoQ ratio and recues the encephalopathic phenotype in Coq9R239X mice
Coenzyme Q (CoQ) deficiency has been associated with primary defects in the CoQ biosynthetic pathway or to secondary events. In some cases, the exogenous CoQ supplementation has limited efficacy. In the Coq9R239X mouse model with fatal mitochondrial encephalopathy due to CoQ deficiency, we have tested the therapeutic potential of b-resorcylic acid (b-RA), a structural analog of the CoQ precursor 4-hydroxybenzoic ... Read more

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