_BACKGROUND_: Histopathological differentiation between BCH and HGPIN in prostatic needle biopsies is a diagnostic challenge. The gold standard for detection of HGPIN and BCH is histopathological examination; however subjectivity in interpretation and tiny volume of obtained tissue hamper reliable diagnosis. _AIMS_: The aim of this study was to assess usefulness of using the p63 and P504s to solve this problem. ... Read more