ABSTRACT OBJECTIVE: To determine the role of secular trend in preeclampsia. MATERIALS AND METHODS: Both at puberty and in the 3rd trimester of 65 singleton-primigravid preeclapmtics (Group I) and 867 comparable healthy, pregnants (Group II), body mass index (BMI), serum testosterones (total & free), dehydroepiandrosterone sulfate, estradiol and sex hormone-binding globulin levels were measured. Also, the ages at menarche, umbilical ... Read more