BACKGROUND: Breast cancer is the most common cancer in Egyptian women. COX-2 seems to be involved in malignant transformation and tumor progression by affecting cell proliferation, mitosis, cell adhesion, apoptosis, immune surveillance, and angiogenesis. Angiogenesis is an important key step in tumor progression. Microvascular density (MVD), a surrogate marker of angiogenesis can be assessed by CD31 staining. AIMS This study ...
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