Adaptive optics scanning light ophthalmoscopy (AOSLO) allows noninvasive assessment of the cone photoreceptor mosaic. Confocal AOSLO imaging of patients with achromatopsia (ACHM) reveals an altered reflectivity of the remaining cone structure, making identification of the cells more challenging than in normal retinas. Recently, a “split-detector” AOSLO imaging method was shown to enable direct visualization of cone inner segments in patients ...
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