ABSTRACT: Surgical trauma elicits a characteristic response involving synthesis and release of acute phase proteins as interleukin-6 (IL-6) and C-reactive protein (CRP). The magnitude of trauma is directly proportionate to the concentration of these mediators. Laparoscopic cholecystectomy is now considered the gold standard for treatment of cholecystolithiasis. We aimed at comparing the magnitude of trauma elicited by laparoscopic versus open ... Read more