nuclear galectin-3 overexpression inversely correlates with lymph node metastasis in lung adenocarcinomas
Multi-functional galecin-3 is found in the nucleus as well as in the cytoplasm. In order to clarify the role of galectin-3 in progression of lung tumors we here immunohistochemically investigated levels in 300 non-small cell lung cancers (NSCLCs), 164 adenocarcinomas (ACs) and 136 squamous cell carcinomas (SCCs), using a monoclonal antibody, Galectin-3 was found to be overexpressed in the nucleus ... Read more