nohafoud

Noha Abdelmageed

Lecturer - lecturer

Faculty of Veterinary Medicine

Address: Fculty of veterinary Medicine, pharmacology department

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Publications Which contain the keyword: tamoxifen

Tamoxifen magnifies therapeutic impact of ceramide in human colorectal cancer cells independent of p53.

2019-02-08 01:08:26 Keywords Colorectal cancer, Ceramide, P53, tamoxifen, P-glycoprotein,
Tamoxifen magnifies therapeutic impact of ceramide in human colorectal cancer cells independent of p53.
Poor prognosis in patients with later stage colorectal cancer (CRC) necessitates the search for new treatment strategies. Ceramide, because of its role in orchestrating death cascades in cancer cells, is a versatile alternative. Ceramide can be generated by exposure to chemotherapy or ionizing radiation, or it can be administered in the form of short-chain analogs (C6-ceramide). Because intracellular P-glycoprotein (P-gp) ... Read more

Efficacy of Tamoxifen and L- carnitine on Sperm Ultrastructure and Seminal Oxidative Stress in patients with idiopathic Oligoasthenoteratozoospermia.

2018-09-29 18:36:40 Keywords ultrastructure, tamoxifen, Oxidative stress, L-carnitine, iOAT,
Efficacy of Tamoxifen and L- carnitine on Sperm Ultrastructure and Seminal Oxidative Stress in patients with idiopathic Oligoasthenoteratozoospermia.
Idiopathic oligoathenoteratozoospermia (iOAT) is a common finding in the evaluation of male infertility. Oxidative stress (OS) may underlie its pathology. Tamoxifen and L-carnitine are used to treat idiopathic male infertility. The aim of this work was to detect the efficacy of tamoxifen and L-carnitine on sperm parameters, sperm ultrastructure and seminal OS in iOAT patients. Sixty patients were recruited for ... Read more

Efficacy of Medical Treatment in the form of Tamoxifen, Oral Zinc and (Diosmin and Hesperidin) in varicocele patients presenting with oligoasthenoteratozoospermia.

2018-10-01 23:40:03 Keywords tamoxifen, Oral Zinc, varicocele, oligoasthenoteratozoospermia, (Diosmin and Hesperidin),
Efficacy of Medical Treatment in the form of Tamoxifen, Oral Zinc and (Diosmin and Hesperidin) in varicocele patients presenting with oligoasthenoteratozoospermia.
Objectives: Varicocele is the most common cause of male infer- tility. It affects spermatogenesis by multiple theories, the most recent is by increasing the levels of reactive oxygen species. Medical treatment in the form of tamoxifen, anti-oxidant (Zinc) and MPFF (Micronised purified flavonoid fractions), may improve sper- matogenesis and semen parameters in patients with varicocele. Our study aims to show ... Read more

Efficacy of Tamoxifen and L- carnitine on Sperm Ultrastructure and Seminal Oxidative Stressin patients with idiopathic Oligoasthenoteratozoospermia.

2018-10-02 00:07:43 Keywords tamoxifen, L- carnitine, Sperm Ultrastructure, Seminal Oxidative Stress, Oligoasthenoteratozoospermia.,
Efficacy of Tamoxifen and L- carnitine on Sperm Ultrastructure and Seminal Oxidative Stressin patients with idiopathic Oligoasthenoteratozoospermia.
OBJECTIVE: Idiopathic oligoathenoteratozoospermia (iOAT) is a common finding in male infertility evaluation. Oxidative stress (OS) may underlie its pathology. Tamoxifen and L-carnitine are used to treat idiopathic male infertility. Aim of this work is to detect the efficacy of tamoxifen and L-carnitine on sperm parameters, sperm ultrastructure and seminal OS in iOAT patients. MATERIAL AND METHODS: 60 patients were recruited ... Read more

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