The world is now facing a pandemic of the novel Corona virus (COVID-19), medical experts are puzzled and searching for some explanation. It is the responsibility of all of us working in the medical field to observe, think, and ask to inspire those who are more specialized in dealing with this disaster. On 30 January 2020, WHO announced the 2019‐nCoV epidemic a public health emergency of international concern. On 11 February 2020, the WHO formally named the disease triggered by 2019‐nCoV as coronavirus disease 2019 (COVID‐19). Looking at a world map showing the prevalence of COVID-19, we can find that Countries where malaria and mosquitoes are endemic have the lowest rates of COVID-19. With the exclusion of countries where malaria never existed or disappeared without specific measures, we will find that countries which take strict measures to eradicate malaria or arboviruses are most affected by COVID-19. Are mosquitoes capable of changing human immune response? A significant number of studies cover the answer to this question.