Colorectal cancer is one of the third leading causes of
cancer mortality worldwide. There is increasing evidences
about the involvement of gut microbiota in colorectal
carcinogenesis. Several recent studies have shed light on
the cross talk between gut microbiota and mucosal T cell
subsets, specically intraepithelial lymphocytes and
lamina propria CD4+ T cells including T-helper cells and T-
regulatory (Treg) cells which may be responsible for
development of colorectal cancer through creang
imbalance between proinammatory and an-
inammatory immune cells and their cytokines. In this
review, we will focus on the inuence gut microbiota on
the development of mucosal T cells and their role in
promong colorectal cancer


(PDF) Interplay between Gut Microbiota and T Lymphocytes in Colorectal Cancer. Available from: https://www.researchgate.net/publication/322310944_Interplay_between_Gut_Microbiota_and_T_Lymphocytes_in_Colorectal_Cancer [accessed Sep 12 2018].