Purpose: To investigate the association among central corneal thickness,
peripheral corneal thickness (PCT), and wavefront aberrations in the
anterior cornea, posterior cornea and the whole eye in myopia.
Methods: Sixty-four eyes of 64 myopic subjects were evaluated with a
Pentacam rotating Scheimpflug camera (Oculus, Inc., WA) corneal topographer
for: (1) wavefront aberrations from the anterior and posterior
corneal surface, (2) corneal thickness (central and peripheral), and (3) with
a wavefront aberration-supported cornea ablation wavefront analyzer (Wavescan,
Visx, Inc., Santa Clara, CA) for wavefront aberrations generated in
the whole eye. Relationships between the wavefront aberrations and
corneal thickness were analyzed.
Results: The mean age of subjects was 34.75 10.08 years. The central
corneal thickness was 550.5 28.459 m. The mean peripheral thickness
was 629.9 32.1 m. Central and PCTs were not significantly correlated
with corneal or ocular high-order aberrations. Intraocular pressure was
significantly correlated with ocular trefoil (r 0.307, P0.001).
Conclusions: Central and PCT were not significantly associated with
either anterior or posterior corneal Zernike aberrations; in addition, no
association with the whole ocular wavefront aberrations was found.