Purpose. To evaluate the corneal endothelial cell density and morphology in normal Egyptian eyes. Methods. In total, 568 healthy
eyes of 568 Egyptian volunteers aged 20 to 85 years were examined using noncontact specular microscopy for the central corneal
thickness (CCT), mean endothelial cell density (MCD), coefficient of variation (CV) in cell area, mean cell area (MCA), and
hexagonal cell (Hex) percentage. Variables were compared between sexes and between different age groups. Results. 'e mean
CCT, MCD, and MCA were 514.45 ± 43.04 μm, 2647.50 ± 382.62 cells/mm2, and 390.59 ± 149.94 μm2, respectively. MCD and
MCA showed no significant differences between men and women (P � 0.171 and 0.099, respectively), whereas CV (%) and Hex
(%) showed significant differences (P � 0.024 and 0.015, respectively). CCT (P � 0.007, r � −0.113) and MCD (P < 0.001,
r � −0.357) exhibited a significant negative correlation with age, whereas CV (%) (P < 0.001, r � 0.341) and MCA (P � 0.008,
r � 0.111) exhibited a significant positive correlation. 'e mean rate of endothelial cell loss from 20 to 85 years of age was 0.3% per
year. Conclusions. Our results provide normative data for the corneal endothelium in healthy Egyptian eyes, thus increasing the
knowledge base for corneal endothelial cell parameters in healthy Egyptian eyes. Furthermore, our findings can be used as baseline
values for comparisons between Egyptian and other populations and for studies of the endothelial cell reserve and capacity for
intraocular surgery and corneal transplantation.