Purpose: To assess the visual outcome and refractive error following wavefront-optimized
(WFO) laser in situ keratomileusis (LASIK) retreatment after previous wavefront-guided (WFG) LASIK
in myopic patients.
Methods: A retrospective analysis of 19 eyes (14 patients) following WFO LASIK retreatment
after previous WFG LASIK that did not give desired refractive results was conducted. The primary
LASIK procedures were performed using the Visx CustomVue™ laser with WFG technology. All of the
subsequent retreatment LASIK procedures were performed with the Wavelight Allegretto™ Eye-Q 400
excimer laser using WFO. Ophthalmic evaluations including uncorrected visual acuity (UCVA), best
spectacle corrected visual acuity (BSCVA), and manifest refraction spherical equivalent (MRSE) were
performed at baseline and postoperatively at 1, 3, 6 months. Pre-retreatment total root mean square
(RMS) from third to sixth order- Zernike polynomials was calculated. Post-retreatment RMS was not
determined.
Results: UCVA and BSCVA improved following retreatment from 0.27±0.18 and 0.0±0.05 to
0.01±0.05 and -0.03±0.05 respectively at 6 months (p<0.001 and p=0.38). The MRSE decreased from -0.5 D
pre-retreatment to -0.2 D at 6 months post-retreatment. The pre-retreatment total HOA was 0.48±0.21 (0.24 to
1.01μm) and did not show correlation with the visual outcomes postoperatively. No intra-operative or postoperative
complications occurred.
Conclusions: The results of these analyses indicate that WFO LASIK retreatment provide satisfactory
refractive and visual acuity results that were not originally achieved with primary WFG LASIK. Retreatment
with WFO LASIK is safe and the results are predictable.
Key Words: Laser in situ keratomileusis (LASIK); retreatment