Abstract The study aimed to determine mean central
corneal thickness (CCT) in a southern Egyptian
population according to gender and age using ultrasonic
pachymetry and to compare these CCT measurements
to different populations. A prospective,
observational, consecutive case series of 4,368 nonglaucomatous
subjects (emmetropes and myopes)
aged 16–70 years was carried out from August 2010
to March 2013 at the outpatient ophthalmology clinic
in Sohag University Hospital and the Laser Vision
Center in Sohag City, Egypt. Refraction, keratometry,
slit-lamp examination, and intraocular pressure (IOP)
measurements were obtained for all subjects. CCT was
measured by ultrasonic pachymetry. The average CCT
was 530.06 ± 38.03 lm. Average CCT was 532.6 ±
33.3 lm in emmetropes, 531.5 ± 31.3 lm in myopes
\6 diopters (D), 531.1 ± 31.4 lm in myopes[6 D
and 533 ± 33 lm in hyperopes, with no statistically
significant difference between the groups. There was a
statistically significant difference in CCT between age
groups and gender. There was a strong correlation
between CCT and IOP among the non-glaucomatous
population. CCT was found to be lower in Egyptians
than in Caucasian, Hispanic, and Japanese populations
but comparable to African and African American
populations.