Objective: To evaluate the effect of preoperative and postoperative keratometry on the visual outcome after laser in situ keratomileusis (LASIK) for moderate and high myopia.

Methods: Records of 812 eyes (420 patients) with myopia ≥ - 6D who had LASIK at Sohag Laser center, Egypt; from January 2010 to November 2013 were retrospectively analyzed. Main outcome measures were postoperative corrected distance visual acuity (CDVA), postoperative spherical equivalence and post operative Q factor.

Results: LASIK was performed in 812 eyes (mean age 21.8 ± 5.2). Patients were grouped according to the degree of preoperative myopia into three groups based: Group 1: -6 D to -7.9 D; Group 2: -8 to -9.9 D; Group 3: -10 to -12 D. The refractive outcome among the different myopia groups, were stratified by pre- and postoperative keratometry. A trend toward greater undercorrection was noted in eyes with preoperative keratometry <43.5 D than in those with steeper keratometry >46 D in all myopia groups. The undercorrecion was also noted in postoperative keratometry groups < 35 D.

Conclusion: Preoperative and postoperative keratometry appeared to influence the refractive outcome especially in high myopic eyes.