Current research has been focused on the influence of land use on Fe and Mn status inSohag governorate soils, South Egypt. Soils were sampled from sites including the cultivatedfloodplain, reclaimed lands, Wadi deposits and the wastewater farmlands at El-Dair, and El-Kola. Forthese samples total and DTPA-extractable Fe and Mn were determined. Total Fe ranges 3.7-9.3%, 1.3-12.3%, 2.5-5.9% and 1.9-7.0% in cultivated floodplain, reclaimed, wadi deposits and wastewaterfarmland at El-Kola, respectively. Total Mn in the cultivated floodplain and reclaimed lands rangedfrom 604 to 2193 mg kg-1 and from 275 to 3505 mg kg-1 respectively, while, in wadi deposits isoscillating in the range 449-1181 mg kg-1. Fe and Mn exhibits positive correlation with clay andorganic matter content while it is negatively correlated with the carbonate content. The wastewaterdisposal practice leads to abnormally elevated values of the available Fe in the reclaimed lands. Inthe lands applied for wastewater disposal at El-Kola and El-Dair, available Fe ranges from 3.5 to526.0 mg kg-1 and 25.4-878.3 mg kg-1 respectively. This suggests wastewater disposal increased therisk of Fe loss to under ground water. Available Mn in cultivated floodplain soils ranges from 17.9to 142.3 mg kg-1, but in the reclaimed lands and wadi deposit range from 4.3 to 269.0 and from 1.66to 144.7 mg kg-1 respectively. The wastewater disposal practice has no marked effect on the soilcontent of available Mn.