Reliability of pulse oximetry during cardiopulmonary resuscitation in a piglet model of neonatal cardiac arrest

Pulse oximetry is widely used in intensive care and emergency conditions to monitor arterial oxygenation and to guide oxygen therapy.

To study the reliability of pulse oximetry in comparison with CO-oximetry in newborn piglets during cardiopulmonary resuscitation (CPR).

In a prospective cohort study in 30 healthy newborn piglets, cardiac arrest was induced, and thereafter each piglet received CPR for 20 min. Arterial oxygen saturation was monitored continuously by pulse oximetry (SpO 2). Arterial blood was analyzed for functional oxygenation (SaO 2) every 2 min. SpO 2 was compared with coinciding SaO 2 values and bias considered whenever the difference (SpO 2-SaO 2) was beyond±5%.

Bias values were decreased at the baseline measurements (mean: 2.5±4.6%) with higher precision and accuracy compared with values across the experiment. Two minutes …