Background and aims: Gastro-oesophageal reflux symptoms are common in different populations. Heartburn and acid regurgitation are the cardinal symptoms of GERD. However, little is known about the prevalence and symptom pattern of GERD in the Egyptian community. We aimed to study the frequency and risk factors of GERD symptoms in patients attending the Tropical Medicine and Gastroenterology and the Internal Medicine outpatients clinics at Sohag University Hospital whatever their chief complaint. Patient and METHODS: 660 consecutive who first attended the out patients Tropical medicine and Gastroenterology outpatient clinic and internal medicine outpatient clinic at Sohag University Hospital , were asked to respond to the F-scale questionnaire regardless of their chief complaints. RESULTS: Of 660 subjects, 374 (56.7%) patient were identified as GERD according to their F-scale score (>7). Although GERD symptoms are common in adults of all ages, the prevalence of GERD was highest in the 40-50 years age group and the age group >60 years had the lowest prevalence for both males and females. The relation of risk factors to the presence or absence of GERD, we found that there is significance difference between GERD and non GERD group as regarding pregnancy (75.0%), drinking coffee and tea (65.0%), eating spicy foods (67.0%) and drugs as NSAIDS (70.8%) (P value= 0.000). But there is no significant difference as regarding gender (p value= 0.374) and smoking (p value= 0.420). Conclusions: GERD symptoms are common in Egyptian outpatients. Using the F-scale questionnaire is easy and useful for epidemiologic studies. Coffee, tea, spicy food, NSAID and pregnancy are risk factors for GERD in this population. Life style modification is essential for management of GERD in our population.