oBjectives: Contrast-induced nephropathy (CIN) has been the third leading cause
of hospital-acquired renal failure. Patients with cardiac diseases are particularly at
risk especially when repeated injections of contrast media are often required. CIN
is generally defined as an increase in serum creatinine concentration of ≥0.5 mg/dL
(≥44 μmol/L) or 25% above baseline within 48 hours after contrast administration.
The aim of this work is to determine the frequency of (CIN ) after cardiac catheterization at Cardiac Catheterization Unit of Sohag University Hospital (Upper
Egypt) and to identify risk factors for (CIN ) in these patients. Methods:The study
included 104 patients attending Sohag University Hospital’s Catheterization Unit
for cardiac catheterization (coronary angiography or percutaneous coronary intervention) with a mean age. 56.11. ±10. Serum creatinin was tested before and after
48hrs following procedure. Coronary angiography was done in the standard fashion.Standard coronary views were obtained, and intervention was done whenever
indicated. results: Patients were subdivided at the end of the study according
to occurrence of (CIN) into two groups: Group A: Included 91 patients who did not
develop (CIN) after coronary catheterization and Group B: Included 13 patients who
developed (CIN) after coronary catheterization, The overall incidence of CIN is12.5%.
CIN increases with older age, particularly above the age of 60 years. There is increase
in the incidence of CIN in diabetics versus non diabetics (20.5% and 6.7%) respectively. There is a highly significant increase in incidence of CIN in patients with CHF
versus those without CHF (100% and 71%) respectively.Patients on diuretics show
significant increase in the incidence of CIN representing 61.5% of all patients who
developed CIN. conclusions: Older patients, diabetic patients, patients with CHF
and patients on diuretics have higher risk of developing CIN during coronary catheterization and should receive reno protective measures before contrast exposure